The active ingredient in Pitcher is garlic extract. Contained within the active ingredient are a unique range of Diallyl polysulfides (DAS). It is these compounds that provide the lethal biochemistry.
- When a Vine Weevil egg or early stage instar encounters Diallyl polysulfide (DAS) molecules they penetrate through the skin
- Rate of passage through the cuticle is dependent on sulphur chain length
- Once the DAS dissolve through the cuticle of the organism the lethal biochemistry starts
- This leads to a cascade chain reaction within the organism which it can't regulate causing it to die due to overwhelming oxidative stress
- Rate of passage through the cuticle is dependent on sulphur chain length
- The action of DAS is initiated following a reaction with intracellular low molecular weight thiols (LMT's) and protein thiols in the organism
- The oxidative stress affects many cellular processes so it is very unlikely that resistance could ever evolve to the chemistry
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